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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731071
Species: Homo sapiens
RGD Object: Gene
Symbol: AHR
Name: aryl hydrocarbon receptor
Acc ID: CHEBI:70159
Term: (+)-(S)-ar-turmerone
Definition: A sesquiterpenoid that is 2-methylhept-2-en-4-one substituted by a 4-methylphenyl group at position 6. It has been isolated from Peltophorum dasyrachis.
Chemical ID: MESH:C078098
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
AHRincreases activityEXP 6480464CTDar-turmerone results in increased activity of AHR proteinPMID:29191726
AHRmultiple interactionsEXP 6480464CTDar-turmerone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]PMID:29191726
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