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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70500
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapk1
Name: mitogen activated protein kinase 1
Acc ID: CHEBI:7005
Term: morusin
Definition: An extended flavonoid that is flavone substituted by hydroxy groups at positions 5, 2' and 4', a prenyl group at position 3 and a 2,2-dimethyl pyran group across positions 7 and 8.
Chemical ID: MESH:C057451
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk1increases phosphorylationISOMAPK1 (Homo sapiens)6480464CTDmorusin results in increased phosphorylation of MAPK1 proteinPMID:33035517
Mapk1multiple interactionsISOMAPK1 (Homo sapiens)6480464CTDAcetylcysteine inhibits the reaction [morusin results in increased phosphorylation of MAPK1 protein]PMID:33035517
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