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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69169
Species: Mus musculus
RGD Object: Gene
Symbol: Pparg
Name: peroxisome proliferator activated receptor gamma
Acc ID: CHEBI:69832
Term: osthole
Definition: A botanical anti-fungal agent that has formula C15H16O3.
Chemical ID: MESH:C046627
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ppargincreases expressionEXP 6480464CTDosthol results in increased expression of PPARG mRNA; osthol results in increased expression of PPARG proteinPMID:19682441
Ppargmultiple interactionsEXP 6480464CTDosthol inhibits the reaction [Isoproterenol results in decreased expression of PPARG mRNA]PMID:21854795
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