GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Gsr | decreases expression | ISO | Gsr (Rattus norvegicus) | 6480464 | CTD | Monocrotaline results in decreased expression of GSR mRNA; Monocrotaline results in decreased expression of GSR protein | PMID:29908794 | Gsr | increases activity | ISO | Gsr (Rattus norvegicus) | 6480464 | CTD | Monocrotaline results in increased activity of GSR protein | PMID:31407471 | Gsr | multiple interactions | ISO | Gsr (Rattus norvegicus) | 6480464 | CTD | Curcumin analog inhibits the reaction [Monocrotaline results in increased activity of GSR protein]; liquiritigenin inhibits the reaction [Monocrotaline results in decreased expression of GSR mRNA]; liquiritigenin inhibits the reaction [Monocrotaline results in decreased expression of GSR protein]; liquiritin inhibits the reaction [Monocrotaline results in decreased expression of GSR mRNA]; liquiritin inhibits the reaction [Monocrotaline results in decreased expression of GSR protein] | PMID:29908794 PMID:31407471 | | ||||||||||||||||||||||
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