GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mmp9 | increases expression | EXP | | 6480464 | CTD | Monocrotaline results in increased expression of MMP9 protein | PMID:29908794 PMID:31504964 PMID:31589899 | Mmp9 | multiple interactions | EXP | | 6480464 | CTD | [Monocrotaline co-treated with LGALS3 protein] inhibits the reaction [[Monocrotaline co-treated with TGFB1] results in decreased expression of MMP9 protein]; [Monocrotaline co-treated with LGALS3 protein] results in decreased expression of MMP9 protein; [Monocrotaline co-treated with TGFB1] results in decreased expression of MMP9 protein; liquiritigenin inhibits the reaction [Monocrotaline results in increased expression of MMP9 protein]; liquiritin inhibits the reaction [Monocrotaline results in increased expression of MMP9 protein] | PMID:27870162 PMID:29908794 PMID:31589899 | Mmp9 | increases expression | ISO | Mmp9 (Mus musculus) | 6480464 | CTD | Monocrotaline results in increased expression of MMP9 mRNA; Monocrotaline results in increased expression of MMP9 protein | PMID:31504964 PMID:33122006 | Mmp9 | multiple interactions | ISO | Mmp9 (Mus musculus) | 6480464 | CTD | [TBXA2R protein affects the susceptibility to Monocrotaline] which affects the expression of MMP9 mRNA; romiplostim inhibits the reaction [Monocrotaline results in increased expression of MMP9 mRNA]; THPO protein inhibits the reaction [Monocrotaline results in increased expression of MMP9 mRNA]; TLR4 gene mutant form inhibits the reaction [Monocrotaline results in increased expression of MMP9 protein] | PMID:31470032 PMID:31504964 PMID:33122006 | | ||||||||||||||||||||||
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