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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2280
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cav1
Name: caveolin 1
Acc ID: CHEBI:6980
Term: monocrotaline
Definition: A pyrrolizidine alkaloid that has formula C16H23NO6.
Chemical ID: MESH:D016686
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cav1decreases expressionEXP 6480464CTDMonocrotaline results in decreased expression of CAV1 mRNA; Monocrotaline results in decreased expression of CAV1 proteinPMID:24835767 PMID:25275723
Cav1multiple interactionsEXP 6480464CTDNCP-2454 inhibits the reaction [Monocrotaline results in decreased expression of CAV1 protein]PMID:25275723
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