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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1587390
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Prkg1
Name: protein kinase cGMP-dependent 1
Acc ID: CHEBI:6980
Term: monocrotaline
Definition: A pyrrolizidine alkaloid that has formula C16H23NO6.
Chemical ID: MESH:D016686
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDMonocrotaline results in decreased expression of PRKG1 protein

PMID:21619414
multiple interactionsEXP 6480464CTDFluoxetine inhibits the reaction [Monocrotaline results in decreased expression of PRKG1 protein]

PMID:21619414
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