Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619831
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fas
Name: Fas cell surface death receptor
Acc ID: CHEBI:69746
Term: alpinumisoflavone
Definition: An isoflavanone that has formula C20H16O5.
Chemical ID: MESH:C000154
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fasincreases expressionISORGD:13462666480464CTDalpinumisoflavone results in increased expression of FAS protein

PMID:23850732
Fasmultiple interactionsISORGD:13462666480464CTD[alpinumisoflavone results in increased expression of FAS protein] which results in increased cleavage of CASP3 protein [alpinumisoflavone results in increased expression of FAS protein] which results in increased cleavage of CASP9 protein

PMID:23850732
Go Back to source page   Continue to Ontology report