GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | AR | affects binding | EXP | | 6480464 | CTD | Mitotane binds to AR protein | PMID:14579009 | AR | multiple interactions | EXP | | 6480464 | CTD | Mitotane binds to and results in decreased activity of AR protein; Mitotane inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Mitotane inhibits the reaction [Dihydrotestosterone binds to AR protein] | PMID:14579009 PMID:33049310 PMID:9705896 | AR | affects binding | ISO | Ar (Rattus norvegicus) | 6480464 | CTD | Mitotane binds to AR protein | PMID:14565775 | |
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