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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70835
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP11B1
Name: cytochrome P450 family 11 subfamily B member 1
Acc ID: CHEBI:6954
Term: Mitotane
Definition: null
Chemical ID: MESH:D008939
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP11B1decreases expressionEXP 6480464CTDMitotane results in decreased expression of CYP11B1 proteinPMID:23696597
CYP11B1increases expressionEXP 6480464CTDMitotane results in increased expression of CYP11B1 mRNAPMID:19900470 PMID:22546480
CYP11B1multiple interactionsEXP 6480464CTDMitotane affects the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP11B1 mRNA]PMID:22546480
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