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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620784
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tnfsf11
Name: TNF superfamily member 11
Acc ID: CHEBI:69499
Term: Bergenin
Definition: A trihydroxybenzoic acid that has formula C14H16O9.
Chemical ID: MESH:C006741
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnfsf11multiple interactionsISORGD:15516556480464CTD[TNFSF11 protein co-treated with Pyruvaldehyde co-treated with bergenin] results in decreased expression of MMP9 mRNA bergenin inhibits the reaction [[TNFSF11 protein co-treated with Pyruvaldehyde] results in decreased activity of ACP5 protein] bergenin inhibits the reaction [[TNFSF11 protein co-treated with Pyruvaldehyde] results in decreased expression of GLO1 protein] bergenin inhibits the reaction [[TNFSF11 protein co-treated with Pyruvaldehyde] results in increased expression of AKT2 mRNA] bergenin inhibits the reaction [[TNFSF11 protein co-treated with Pyruvaldehyde] results in increased expression of MAPK3 mRNA] bergenin inhibits the reaction [[TNFSF11 protein co-treated with Pyruvaldehyde] results in increased expression of OSTM1 mRNA]

PMID:31369791
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