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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1344192
Species: Homo sapiens
RGD Object: Gene
Symbol: TNF
Name: tumor necrosis factor
Acc ID: CHEBI:69499
Term: Bergenin
Definition: A trihydroxybenzoic acid that has formula C14H16O9.
Chemical ID: MESH:C006741
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TNFmultiple interactionsISOTnf (Mus musculus)6480464CTDbergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased secretion of TNF protein]PMID:37482253
TNFmultiple interactionsISOTnf (Rattus norvegicus)6480464CTD[bergenin co-treated with 2,2-bis(4-glycidyloxyphenyl)propane] inhibits the reaction [Sodium Azide results in increased expression of TNF protein]; [Sodium Azide co-treated with bergenin] results in increased expression of TNF protein; bergenin inhibits the reaction [Cadmium results in increased expression of TNF protein]; bergenin inhibits the reaction [Iron-Dextran Complex results in increased expression of TNF protein]PMID:36207002 PMID:36249784 PMID:37949422
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