GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Akt1 | increases expression | EXP | | 6480464 | CTD | Cannabidiol results in increased expression of AKT1 mRNA | PMID:33019509 | Akt1 | affects expression | ISO | AKT1 (Homo sapiens) | 6480464 | CTD | Cannabidiol affects the expression of AKT1 protein | PMID:26504004 | Akt1 | decreases expression | ISO | AKT1 (Homo sapiens) | 6480464 | CTD | Cannabidiol results in decreased expression of AKT1 mRNA | PMID:30713602 | Akt1 | decreases phosphorylation | ISO | AKT1 (Homo sapiens) | 6480464 | CTD | Cannabidiol results in decreased phosphorylation of AKT1 protein | PMID:28392768 PMID:32060308 PMID:36810933 | Akt1 | increases expression | ISO | AKT1 (Homo sapiens) | 6480464 | CTD | Cannabidiol results in increased expression of AKT1 mRNA | PMID:27932991 PMID:28025562 PMID:31801206 | Akt1 | increases phosphorylation | ISO | AKT1 (Homo sapiens) | 6480464 | CTD | Cannabidiol results in increased phosphorylation of AKT1 protein | PMID:33817834 | Akt1 | multiple interactions | ISO | AKT1 (Homo sapiens) | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Cannabidiol results in decreased phosphorylation of AKT1 protein]; [Cannabidiol co-treated with 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one] results in decreased phosphorylation of AKT1 protein; [Oxygen co-treated with Ozone co-treated with Cannabidiol] results in decreased expression of AKT1 mRNA; Acetylcysteine inhibits the reaction [Cannabidiol results in decreased phosphorylation of AKT1 protein]; AM 251 inhibits the reaction [Cannabidiol results in increased phosphorylation of AKT1 protein]; Cannabidiol promotes the reaction [SB 203580 results in decreased phosphorylation of AKT1 protein]; Cannabidiol results in decreased phosphorylation of and results in decreased expression of AKT1 protein modified form; Chloroquine affects the reaction [Cannabidiol results in decreased phosphorylation of AKT1 protein]; LAIR1 protein affects the reaction [Cannabidiol results in decreased phosphorylation of AKT1 protein]; tanespimycin affects the reaction [Cannabidiol affects the expression of AKT1 protein]; VER 155008 affects the reaction [Cannabidiol affects the expression of AKT1 protein] | PMID:26504004 PMID:32060308 PMID:32992648 PMID:33817834 PMID:34575494 PMID:36810933 | |
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