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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1317785
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp2c65
Name: cytochrome P450, family 2, subfamily c, polypeptide 65
Acc ID: CHEBI:69478
Term: cannabidiol
Definition: An cannabinoid that is cyclohexene which is substituted by a methyl group at position 1, a 2,6-dihydroxy-4-pentylphenyl group at position 3, and a prop-1-en-2-yl group at position 4.
Chemical ID: MESH:D002185
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2c65multiple interactionsEXP 6480464CTD[Plant Extracts results in increased abundance of Cannabidiol] which results in increased expression of CYP2C65 mRNAPMID:33096940
Cyp2c65decreases activityISOCYP2C9 (Homo sapiens)6480464CTDCannabidiol results in decreased activity of CYP2C9 proteinPMID:24667653
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