Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1347686
Species: Homo sapiens
RGD Object: Gene
Symbol: NANOG
Name: Nanog homeobox
Acc ID: CHEBI:69355
Term: casticin
Definition: A tetramethoxyflavone that consists of quercetagetin in which the hydroxy groups at positions 3, 6, 7 and 4' have been replaced by methoxy groups. It has been isolated from Eremophila mitchellii.
Chemical ID: MESH:C054133
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NANOGdecreases expressionEXP 6480464CTDcasticin results in decreased expression of NANOG mRNAPMID:32268151
NANOGmultiple interactionsEXP 6480464CTDcasticin promotes the reaction [MIR148A mRNA results in decreased expression of NANOG mRNA]; DNMT1 protein inhibits the reaction [casticin results in decreased expression of NANOG protein]; MIR148A mRNA promotes the reaction [casticin results in decreased expression of NANOG mRNA]PMID:32268151
Go Back to source page   Continue to Ontology report