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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619788
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Trpc6
Name: transient receptor potential cation channel, subfamily C, member 6
Acc ID: CHEBI:69251
Term: (+)-conocarpan
Definition: A member of the class of benzofurans that is 2,3-dihydro-1-benzofuran substituted by a methyl group at position 3, a prop-1-en-1-yl group at position 5 and a 4-hydroxyphenyl group at position 2. It is a lignan derivative isolated from the roots of Krameria lappacea.
Chemical ID: MESH:C447284
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Trpc6increases activityISORGD:7327216480464CTDconocarpan results in increased activity of TRPC6 protein

PMID:31054997
Trpc6multiple interactionsISORGD:7327216480464CTDSAR7334 inhibits the reaction [conocarpan results in increased activity of TRPC6 protein]

PMID:31054997
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