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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69368
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Scn9a
Name: sodium voltage-gated channel alpha subunit 9
Acc ID: CHEBI:6916
Term: mexiletine
Definition: An aromatic ether which is 2,6-dimethylphenyl ether of 2-aminopropan-1-ol.
Chemical ID: MESH:D008801
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Scn9aincreases response to substanceISORGD:7371516480464CTDSCN9A mRNA SNP results in increased susceptibility to Mexiletine

PMID:19162012
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