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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2100
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Alpl
Name: alkaline phosphatase, biomineralization associated
Acc ID: CHEBI:6888
Term: 6alpha-methylprednisolone
Definition: The 6alpha-stereoisomer of 6-methylprednisolone.
Chemical ID: MESH:D008775
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Alplincreases secretionEXP 6480464CTDMethylprednisolone results in increased secretion of ALPL proteinPMID:30291735
Alplmultiple interactionsEXP 6480464CTDAlendronate inhibits the reaction [Methylprednisolone results in increased secretion of ALPL protein]; Nebivolol promotes the reaction [Alendronate inhibits the reaction [Methylprednisolone results in increased secretion of ALPL protein]]PMID:30291735
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