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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10916
Species: Mus musculus
RGD Object: Gene
Symbol: Mpo
Name: myeloperoxidase
Acc ID: CHEBI:6888
Term: 6alpha-methylprednisolone
Definition: The 6alpha-stereoisomer of 6-methylprednisolone.
Chemical ID: MESH:D008775
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mpodecreases expressionEXP 6480464CTDMethylprednisolone results in decreased expression of MPO proteinPMID:28557239
Mpomultiple interactionsEXP 6480464CTD[Polymyxin B co-treated with Methylprednisolone] inhibits the reaction [Alpha-Amanitin results in increased activity of MPO protein]; Methylprednisolone inhibits the reaction [Alpha-Amanitin results in increased activity of MPO protein]PMID:30891624
Mpomultiple interactionsISOMpo (Rattus norvegicus)6480464CTDMethylprednisolone inhibits the reaction [Bleomycin results in increased expression of MPO protein]PMID:26093215
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