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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1313525
Species: Homo sapiens
RGD Object: Gene
Symbol: MKI67
Name: marker of proliferation Ki-67
Acc ID: CHEBI:68657
Term: zingerone
Definition: A methyl ketone that is 4-phenylbutan-2-one in which the phenyl ring is substituted at positions 3 and 4 by methoxy and hydroxy groups respectively. The major pungent component in ginger.
Chemical ID: MESH:C013738
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MKI67multiple interactionsISOMki67 (Rattus norvegicus)6480464CTDzingerone inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of MKI67 protein]PMID:30720227
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