GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307098
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Olig2
Name: oligodendrocyte transcription factor 2
Acc ID: CHEBI:68610
Term: linagliptin
Definition: A xanthine that is 7H-xanthine bearing (4-methylquinazolin-2-yl)methyl, methyl, but-2-yn-1-yl and 3-aminopiperidin-1-yl substituents at positions 1, 3, 7 and 8 respectively (the R-enantiomer). Used for treatment of type II diabetes.
Chemical ID: MESH:D000069476
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:13160896480464CTDLinagliptin inhibits the reaction [Cuprizone results in decreased expression of OLIG2 mRNA]

PMID:29864483
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