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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730815
Species: Mus musculus
RGD Object: Gene
Symbol: P2rx7
Name: purinergic receptor P2X, ligand-gated ion channel, 7
Acc ID: CHEBI:68508
Term: diethyl maleate
Definition: A maleate ester resulting from the formal condensation of both carboxy groups of maleic acid with ethanol. A colourless liquid at room temperature (m.p. -10degreeC) with boiling point 220degreeC at 1 atm., it is commonly used as a dienophile for Diels-Alder-type cycloaddition reactions in organic synthesis.
Chemical ID: MESH:C014476
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
P2rx7decreases expressionISOP2rx7 (Rattus norvegicus)6480464CTDdiethyl maleate results in decreased expression of P2RX7 mRNAPMID:21161181
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