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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10796
Species: Mus musculus
RGD Object: Gene
Symbol: Il4
Name: interleukin 4
Acc ID: CHEBI:68508
Term: diethyl maleate
Definition: A maleate ester resulting from the formal condensation of both carboxy groups of maleic acid with ethanol. A colourless liquid at room temperature (m.p. -10degreeC) with boiling point 220degreeC at 1 atm., it is commonly used as a dienophile for Diels-Alder-type cycloaddition reactions in organic synthesis.
Chemical ID: MESH:C014476
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il4multiple interactionsISOIL4 (Homo sapiens)6480464CTD[diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD80 protein; [diethyl maleate co-treated with IL4 protein co-treated with TNF protein co-treated with Ionomycin] results in increased expression of CD86 proteinPMID:31958493
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