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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737448
Species: Mus musculus
RGD Object: Gene
Symbol: Cat
Name: catalase
Acc ID: CHEBI:6842
Term: methoxychlor
Definition: An organochlorine insecticide that has formula C16H15Cl3O2.
Chemical ID: MESH:D008731
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Catdecreases expressionEXP 6480464CTDMethoxychlor results in decreased expression of CAT mRNAPMID:16807286
Catmultiple interactionsEXP 6480464CTDMethoxychlor results in decreased expression of and results in decreased activity of CAT proteinPMID:16890261
Catdecreases activityISOCat (Rattus norvegicus)6480464CTDMethoxychlor results in decreased activity of CAT proteinPMID:12062931 PMID:12451445 PMID:19202561
Catmultiple interactionsISOCat (Rattus norvegicus)6480464CTDVitamin E inhibits the reaction [Methoxychlor results in decreased activity of CAT protein]PMID:11955947
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