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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732251
Species: Homo sapiens
RGD Object: Gene
Symbol: SHANK3
Name: SH3 and multiple ankyrin repeat domains 3
Acc ID: CHEBI:6842
Term: methoxychlor
Definition: An organochlorine insecticide that has formula C16H15Cl3O2.
Chemical ID: MESH:D008731
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SHANK3affects methylationISOShank3 (Rattus norvegicus)6480464CTDMethoxychlor affects the methylation of SHANK3 genePMID:35440735
SHANK3increases methylationISOShank3 (Rattus norvegicus)6480464CTDMethoxychlor results in increased methylation of SHANK3 genePMID:23303685
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