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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62197
Species: Mus musculus
RGD Object: Gene
Symbol: Ptprn2
Name: protein tyrosine phosphatase receptor type N polypeptide 2
Acc ID: CHEBI:6842
Term: methoxychlor
Definition: An organochlorine insecticide that has formula C16H15Cl3O2.
Chemical ID: MESH:D008731
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptprn2affects methylationISOPtprn2 (Rattus norvegicus)6480464CTDMethoxychlor affects the methylation of PTPRN2 genePMID:35440735
Ptprn2increases expressionISOPtprn2 (Rattus norvegicus)6480464CTDMethoxychlor results in increased expression of PTPRN2 mRNAPMID:21782745
Ptprn2multiple interactionsISOPtprn2 (Rattus norvegicus)6480464CTD[Genistein co-treated with Methoxychlor] results in increased expression of PTPRN2 mRNAPMID:21782745
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