GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CYP3A5 | decreases methylation | ISO | Cyp3a9 (Rattus norvegicus) | 6480464 | CTD | CYP3A5 protein results in decreased methylation of Methoxychlor | PMID:12433799 | CYP3A5 | increases expression | ISO | Cyp3a9 (Rattus norvegicus) | 6480464 | CTD | Methoxychlor results in increased expression of CYP3A9 mRNA | PMID:21782745 | CYP3A5 | multiple interactions | ISO | Cyp3a9 (Rattus norvegicus) | 6480464 | CTD | [Genistein co-treated with Methoxychlor] results in increased expression of CYP3A9 mRNA | PMID:21782745 | |
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