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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620396
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Kl
Name: Klotho
Acc ID: CHEBI:68232
Term: (Z)-ligustilide
Definition: A butenolide that has formula C12H14O2.
Chemical ID: MESH:C027820
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Klincreases expressionISORGD:7327836480464CTDligustilide results in increased expression of KL mRNA, ligustilide results in increased expression of KL protein

PMID:23973442
Klincreases expressionISORGD:7327846480464CTDligustilide results in increased expression of KL mRNA, ligustilide results in increased expression of KL protein

PMID:23973442
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.