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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2458
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp1a1
Name: cytochrome P450, family 1, subfamily a, polypeptide 1
Acc ID: CHEBI:68232
Term: (Z)-ligustilide
Definition: A butenolide that has formula C12H14O2.
Chemical ID: MESH:C027820
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp1a1increases expressionISORGD:7308706480464CTDligustilide results in increased expression of CYP1A1 mRNA

PMID:29191726
Cyp1a1multiple interactionsISORGD:7308706480464CTDligustilide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]

PMID:29191726
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