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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2951
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Kcna3
Name: potassium voltage-gated channel subfamily A member 3
Acc ID: CHEBI:6809
Term: methamphetamine
Definition: A member of the class of amphetamines in which the amino group of (S)-amphetamine carries a methyl substituent.
Chemical ID: MESH:D008694
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kcna3increases expressionEXP 6480464CTDMethamphetamine results in increased expression of KCNA3 mRNA; Methamphetamine results in increased expression of KCNA3 proteinPMID:24533129
Kcna3multiple interactionsEXP 6480464CTDmargatoxin inhibits the reaction [Methamphetamine results in increased expression of KCNA3 mRNA]; margatoxin inhibits the reaction [Methamphetamine results in increased expression of KCNA3 protein]PMID:24533129
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