GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bbc3 | increases expression | EXP | | 6480464 | CTD | Methamphetamine results in increased expression of BBC3 protein | PMID:30394308 | Bbc3 | multiple interactions | EXP | | 6480464 | CTD | BBC3 protein promotes the reaction [Methamphetamine results in increased expression of NOS2 protein] | PMID:30394308 | Bbc3 | increases expression | ISO | Bbc3 (Rattus norvegicus) | 6480464 | CTD | Methamphetamine results in increased expression of BBC3 protein | PMID:26524635 PMID:34214594 | Bbc3 | increases expression | ISO | BBC3 (Homo sapiens) | 6480464 | CTD | Methamphetamine results in increased expression of BBC3 mRNA; Methamphetamine results in increased expression of BBC3 protein | PMID:23820845 PMID:26524635 | Bbc3 | multiple interactions | ISO | Bbc3 (Rattus norvegicus) | 6480464 | CTD | 4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased expression of BBC3 protein]; BBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of CASP3 protein]; BBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of PARP1 protein]; BBC3 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; BBC3 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased expression of BBC3 protein] | PMID:26524635 PMID:34214594 | Bbc3 | multiple interactions | ISO | BBC3 (Homo sapiens) | 6480464 | CTD | [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BBC3 mRNA; [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BBC3 protein; BBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of CASP3 protein]; BBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of PARP1 protein]; BBC3 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; BBC3 protein affects the reaction [Methamphetamine results in increased expression of BAX protein] | PMID:23820845 PMID:26524635 | | ||||||||||||||||||||||
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