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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1551097
Species: Mus musculus
RGD Object: Gene
Symbol: Myd88
Name: myeloid differentiation primary response gene 88
Acc ID: CHEBI:6809
Term: methamphetamine
Definition: A member of the class of amphetamines in which the amino group of (S)-amphetamine carries a methyl substituent.
Chemical ID: MESH:D008694
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Myd88increases expressionEXP 6480464CTDMethamphetamine results in increased expression of MYD88 mRNA; Methamphetamine results in increased expression of MYD88 proteinPMID:33359793 PMID:35390362 PMID:35688268 PMID:36720452
Myd88multiple interactionsEXP 6480464CTD[Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of MYD88 mRNA]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of MYD88 protein]; obeticholic acid inhibits the reaction [Methamphetamine results in increased expression of MYD88 protein]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of MYD88 mRNA]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of MYD88 protein]PMID:35390362 PMID:35688268 PMID:36720452
Myd88increases expressionISOMyd88 (Rattus norvegicus)6480464CTDMethamphetamine results in increased expression of MYD88 proteinPMID:30450033
Myd88multiple interactionsISOMyd88 (Rattus norvegicus)6480464CTDLactulose inhibits the reaction [Methamphetamine results in increased expression of MYD88 protein]PMID:30450033
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