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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69009
Species: Mus musculus
RGD Object: Gene
Symbol: Il13
Name: interleukin 13
Acc ID: CHEBI:6801
Term: metformin
Definition: A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.
Chemical ID: MESH:D008687
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il13multiple interactionsEXP 6480464CTDMetformin inhibits the reaction [IL13 protein results in increased expression of ARG1 mRNA]; Metformin inhibits the reaction [IL13 protein results in increased expression of CCL2 mRNA]; Metformin inhibits the reaction [IL13 protein results in increased expression of CCL24 mRNA]; Metformin inhibits the reaction [IL13 protein results in increased expression of CCL7 mRNA]; Metformin inhibits the reaction [IL13 protein results in increased expression of CCR2 mRNA]; Metformin inhibits the reaction [IL13 protein results in increased expression of CHIL3 mRNA]; Metformin inhibits the reaction [IL13 protein results in increased expression of CXCL2 mRNA]; Metformin inhibits the reaction [IL13 protein results in increased expression of EDN1 mRNA]; Metformin inhibits the reaction [IL13 protein results in increased expression of FGF1 mRNA]; Metformin inhibits the reaction [IL13 protein results in increased expression of IGF1 mRNA]; Metformin inhibits the reaction [IL13 protein results in increased expression of IL1B mRNA]; Metformin inhibits the reaction [IL13 protein results in increased expression of MGL2 mRNA]; Metformin inhibits the reaction [IL13 protein results in increased expression of MMP10 mRNA]; Metformin inhibits the reaction [IL13 protein results in increased expression of MMP14 mRNA]; Metformin inhibits the reaction [IL13 protein results in increased expression of MMP9 mRNA]; Metformin inhibits the reaction [IL13 protein results in increased expression of MRC1 mRNA]; Metformin inhibits the reaction [IL13 protein results in increased expression of MRC1 protein]; Metformin inhibits the reaction [IL13 protein results in increased expression of PPARG mRNA]; Metformin inhibits the reaction [IL13 protein results in increased expression of RETNLA mRNA]PMID:26497364
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