GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Igf2r | increases expression | EXP | | 6480464 | CTD | Metformin results in increased expression of IGF2R mRNA | PMID:25596134 | Igf2r | multiple interactions | ISO | IGF2R (Homo sapiens) | 6480464 | CTD | [Metformin co-treated with IGF1 protein] results in decreased expression of IGF2R mRNA; [Metformin co-treated with IGF2 protein] results in decreased expression of IGF2R mRNA; [Metformin co-treated with INS protein] results in decreased expression of IGF2R mRNA | PMID:21664031 | |
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