Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1304627
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Chat
Name: choline O-acetyltransferase
Acc ID: CHEBI:67988
Term: ginsenoside Rd
Definition: A ginsenoside found in Panax ginseng and Panax japonicus var. major that is (20S)-ginsenoside Rg3 in which the hydroxy group at position 20 has been converted to its beta-D-glucopyranoside.
Chemical ID: MESH:C049863
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Chatincreases expressionISORGD:15499906480464CTDginsenoside Rd results in increased expression of CHAT mRNA ginsenoside Rd results in increased expression of CHAT protein

PMID:24599032
Chatmultiple interactionsISORGD:15499906480464CTDstaurosporine aglycone inhibits the reaction [ginsenoside Rd results in increased expression of CHAT mRNA] staurosporine aglycone inhibits the reaction [ginsenoside Rd results in increased expression of CHAT protein]

PMID:24599032
Go Back to source page   Continue to Ontology report