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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620360
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nfe2l2
Name: nuclear factor, erythroid 2-like 2
Acc ID: CHEBI:67897
Term: farrerol
Definition: An organic molecular entity that has formula C17H16O5.
Chemical ID: MESH:C015881
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nfe2l2affects localizationISORGD:7344326480464CTDfarrerol affects the localization of NFE2L2 protein

PMID:26111761
Nfe2l2multiple interactionsISORGD:7344326480464CTD2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [farrerol affects the localization of NFE2L2 protein], NFE2L2 protein promotes the reaction [farrerol results in increased expression of HMOX1 protein], SB 203580 inhibits the reaction [farrerol affects the localization of NFE2L2 protein], U 0126 inhibits the reaction [farrerol affects the localization of NFE2L2 protein]

PMID:26111761
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.