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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619951
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcb1a
Name: ATP binding cassette subfamily B member 1A
Acc ID: CHEBI:67862
Term: coptisine
Definition: An alkaloid that has formula C19H14NO4.
Chemical ID: MESH:C034384
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcb1aincreases expressionEXP 6480464CTDcoptisine results in increased expression of ABCB1A mRNA; coptisine results in increased expression of ABCB1A proteinPMID:20410605
Abcb1amultiple interactionsEXP 6480464CTDDactinomycin inhibits the reaction [coptisine results in increased expression of ABCB1A mRNA]PMID:20410605
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