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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732101
Species: Homo sapiens
RGD Object: Gene
Symbol: KCNH2
Name: potassium voltage-gated channel subfamily H member 2
Acc ID: CHEBI:6780
Term: mesoridazine
Definition: A phenothiazine substituted at position 2 (para to the S atom) by a methylsulfinyl group, and on the nitrogen by a 2-(1-methylpiperidin-2-yl)ethyl group.
Chemical ID: MESH:D008653
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
KCNH2decreases activityEXP 6480464CTDMesoridazine results in decreased activity of KCNH2 proteinPMID:17042915
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