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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732102
Species: Mus musculus
RGD Object: Gene
Symbol: Kcnh2
Name: potassium voltage-gated channel, subfamily H (eag-related), member 2
Acc ID: CHEBI:6762
Term: mepyramine
Definition: An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group.
Chemical ID: MESH:D011738
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kcnh2affects activityISOKCNH2 (Homo sapiens)6480464CTDPyrilamine affects the activity of KCNH2 proteinPMID:16278312
Kcnh2multiple interactionsISOKCNH2 (Homo sapiens)6480464CTDPyrilamine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]PMID:21158687
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