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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732909
Species: Homo sapiens
RGD Object: Gene
Symbol: AKT1
Name: AKT serine/threonine kinase 1
Acc ID: CHEBI:67521
Term: (-)-gambogic acid
Definition: A pyranoxanthone that has formula C38H44O8.
Chemical ID: MESH:C052659
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
AKT1decreases activityEXP 6480464CTDgambogic acid results in decreased activity of AKT1 proteinPMID:19433130
AKT1decreases expressionEXP 6480464CTDgambogic acid results in decreased expression of AKT1 mRNAPMID:33533530
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