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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1608349
Species: Mus musculus
RGD Object: Gene
Symbol: Mir21a
Name: microRNA 21a
Acc ID: CHEBI:67486
Term: quercetin 3-O-beta-D-galactopyranoside
Definition: A quercetin O-glycoside that is quercetin with a beta-D-galactosyl residue attached at position 3. Isolated from Artemisia capillaris, it exhibits hepatoprotective activity.
Chemical ID: MESH:C021304
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mir21amultiple interactionsISOMIR21 (Homo sapiens)6480464CTD[Quercetin co-treated with hyperoside] results in decreased expression of MIR21 mRNA; MIR21 mRNA inhibits the reaction [[Quercetin co-treated with hyperoside] results in increased expression of PDCD4 mRNA]; MIR21 mRNA inhibits the reaction [[Quercetin co-treated with hyperoside] results in increased expression of PDCD4 protein]; MIR21 mRNA results in decreased susceptibility to [Quercetin co-treated with hyperoside]PMID:25354548
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