Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	736217
Species:	Homo sapiens
RGD Object:	Gene
Symbol:	CYP2D6
Name:	cytochrome P450 family 2 subfamily D member 6

Acc ID:	CHEBI:6729
Term:	Melarsoprol
Definition:	A triazine that has formula C12H15AsN6OS2.
Chemical ID:	MESH:D008549

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
CYP2D6	decreases activity	EXP		6480464	CTD	Melarsoprol results in decreased activity of CYP2D6 protein	PMID:11124226

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.