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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733756
Species: Mus musculus
RGD Object: Gene
Symbol: Mmp3
Name: matrix metallopeptidase 3
Acc ID: CHEBI:6723
Term: megestrol acetate
Definition: A steroid ester resulting from the formal condensation of the hydroxy group of megestrol with the carboxy group of acetic acid. It is an appetite stimulant used for the treatment of anorexia and cachexia. Also used for birth control and for the treatment of breast cancer.
Chemical ID: MESH:D019290
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mmp3multiple interactionsISOMmp3 (Rattus norvegicus)6480464CTD[Ethinyl Estradiol co-treated with Megestrol Acetate] results in increased expression of MMP3 proteinPMID:22085904
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