GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CYP1A2 | decreases activity | EXP | | 6480464 | CTD | Mefenamic Acid results in decreased activity of CYP1A2 protein | PMID:18816299 | CYP1A2 | increases glutathionylation | EXP | | 6480464 | CTD | CYP1A2 protein results in increased glutathionylation of Mefenamic Acid analog | PMID:25372302 | CYP1A2 | increases hydroxylation | EXP | | 6480464 | CTD | CYP1A2 protein results in increased hydroxylation of Mefenamic Acid | PMID:25372302 | CYP1A2 | increases oxidation | EXP | | 6480464 | CTD | CYP1A2 protein results in increased oxidation of Mefenamic Acid | PMID:33259822 | CYP1A2 | multiple interactions | EXP | | 6480464 | CTD | SOD1 protein inhibits the reaction [CYP1A2 protein results in increased oxidation of Mefenamic Acid] | PMID:33259822 | |
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