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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3776
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sult1e1
Name: sulfotransferase family 1E member 1
Acc ID: CHEBI:6710
Term: meclofenamic acid
Definition: An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,6-dichloro-3-methylphenyl group. A non-steroidal anti-inflammatory drug, it is used as the sodium salt for the treatment of dysmenorrhoea (painful periods), osteoarthritis and rheumatoid arthritis.
Chemical ID: MESH:D008469
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sult1e1decreases activityISOSULT1E1 (Homo sapiens)6480464CTDMeclofenamic Acid results in decreased activity of SULT1E1 proteinPMID:17073578
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