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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2351
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Chrnb4
Name: cholinergic receptor nicotinic beta 4 subunit
Acc ID: CHEBI:6706
Term: Mecamylamine
Definition: A primary aliphatic amine that has formula C11H21N.
Chemical ID: MESH:D008464
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Chrnb4multiple interactionsEXP 6480464CTDMecamylamine results in decreased activity of [CHRNA3 protein binds to CHRNB4 protein]PMID:11600638 PMID:9687574
Chrnb4multiple interactionsISOChrnb4 (Mus musculus)6480464CTDMecamylamine binds to and results in decreased activity of [CHRNA3 protein binds to CHRNB4 protein]PMID:20100906
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