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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1344835
Species: Homo sapiens
RGD Object: Gene
Symbol: ULK1
Name: unc-51 like autophagy activating kinase 1
Acc ID: CHEBI:66682
Term: maslinic acid
Definition: A pentacyclic triterpenoid that is olean-12-ene substituted by hydroxy groups at positions 2 and 3 and a carboxy group at position 28 (the 2alpha,3beta stereoisomer). It is isolated from Olea europaea and Salvia canariensis and exhibits anti-inflammatory, antioxidant and antineoplastic activity.
Chemical ID: MESH:C412811
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ULK1multiple interactionsISOUlk1 (Mus musculus)6480464CTD[maslinic acid analog co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of ULK1 proteinPMID:26513295
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