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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619934
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp2c6v1
Name: cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1
Acc ID: CHEBI:66651
Term: madecassoside
Definition: A triterpenoid saponin that is a trisaccharide derivative of madecassic acid. Isolated from Centella asiatica, it exhibits anti-inflammatory, antioxidant and antirheumatic activities.
Chemical ID: MESH:C093443
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2c6v1decreases activityISORGD:7374166480464CTDmadecassoside results in decreased activity of CYP2C19 proteinPMID:21349323
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