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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732953
Species: Mus musculus
RGD Object: Gene
Symbol: Slc22a8
Name: solute carrier family 22 (organic anion transporter), member 8
Acc ID: CHEBI:66395
Term: miquelianin
Definition: A quercetin O-glycoside that consists of quercetin attached to a beta-D-glucuronopyranosyl moiety at position 3 via a glycosidic linkage. Isolated from Salvia and Phaseolus vulgaris, it exhibits antioxidant and antidepressant activities.
Chemical ID: MESH:C443401
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc22a8increases uptakeISORGD:7329526480464CTDSLC22A8 protein results in increased uptake of quercetin 3-O-glucuronide analog

PMID:21244849
Slc22a8multiple interactionsISORGD:7329526480464CTDquercetin 3-O-glucuronide analog inhibits the reaction [SLC22A8 protein results in increased transport of 4-carboxyfluorescein] quercetin 3-O-glucuronide inhibits the reaction [SLC22A8 protein results in increased transport of 4-carboxyfluorescein]

PMID:21244849
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