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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736934
Species: Homo sapiens
RGD Object: Gene
Symbol: GSTT1
Name: glutathione S-transferase theta 1
Acc ID: CHEBI:66331
Term: xanthohumol
Definition: A member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 4, 2' and 4', a methoxy group at position 6' and a prenyl group at position 3'. Isolated from Humulus lupulus, it induces apoptosis in human malignant glioblastoma cells.
Chemical ID: MESH:C104536
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GSTT1increases expressionEXP 6480464CTDxanthohumol results in increased expression of GSTT1 mRNA; xanthohumol results in increased expression of GSTT1 proteinPMID:23085367
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